Stress during pregnancy may harm unborn baby's brain, studies find | CNN (2023)

Stress during pregnancy may harm unborn baby's brain, studies find | CNN (1)

Who doesn't want to be happy? —

As research into our mysterious gray matter continues to explode, scientists are getting ever closer to understanding what creates a calm, contented and happy brain. Answer these eight questions to see whether your brain is wired to be happy or if you might need to practice positivity.

Stress during pregnancy may harm unborn baby's brain, studies find | CNN (2)

Q: Which picture appeals to you the most? —

A: If you picked the kitten or pup, your brain may be wired to be happy. Studies show that people who have happy brains respond more to positive things than negative or neutral ones.

Stress during pregnancy may harm unborn baby's brain, studies find | CNN (3)

Q: Which picture is most positive? —

A: All of them. They all have positive elements. No one is hurt, and everyone has access to help. Happy people, according to happiness researcher and author Rick Hanson, look for the positives in each experience and try to hold on to those.

(Video) Stress during pregnancy may harm unborn baby's brain, studies find
Stress during pregnancy may harm unborn baby's brain, studies find | CNN (4)

Q: Which of these is critical to your happiness? —

A: None of them. Happiness researcher Sonja Lyubomirsky says that although all of these can contribute to contentment, they are also part of The Myths of Happiness. She defines those as "myths that assure us that lifelong happiness will be attained once we hit the culturally confirmed markers of adult success. This restricted view of happiness works to discourage us from recognizing the upside of any negative life turn and blocks us from recognizing our own growth potential."

Stress during pregnancy may harm unborn baby's brain, studies find | CNN (5)

Q: What can you practice to be happier? —

A: All of them. Studies tell us that writing down what we are grateful for several times a week, laughing and surrounding ourselves with positive, nurturing relationships and looking for the positive as often as possible are great ways to boost mood.

Stress during pregnancy may harm unborn baby's brain, studies find | CNN (6)

Q: At which age are you most likely to be happy? —

A: Old age. While most people believe happiness declines with age, studies show that's not true. A large Gallup poll found 85-year-olds to be more satisfied with themselves than 18-year-olds, and another study found that happiness and enjoyment dip in middle age and rise again in old age.

(Video) Stressed during pregnancy? Your baby might feel long term effects

Stress during pregnancy may harm unborn baby's brain, studies find | CNN (7)

Q: Which experiences will make you happiest? —

A: It depends on your age. Younger people gain more happiness from uncommon, extraordinary experiences, while older people savor simple, ordinary experiences that fill up daily life.

Stress during pregnancy may harm unborn baby's brain, studies find | CNN (8)

Q: Which of these purchases might make you happiest? —

A: Family games and traveling. Studies show that spending on meaningful activities that bring us closer to family and friends or boost self-confidence makes us the happiest, such as sharing travel experiences, playing board games or learning musical instruments.

Stress during pregnancy may harm unborn baby's brain, studies find | CNN (9)

Q: Which activity could train your brain to be happy? —

A: All of them. In fact, happy brain expert Dr. Richard Davidson says his data show that if a person sits quietly and thinks about kindness and compassion for a half-hour a day, their brain will show noticeable changes in just two weeks.

Q&A: Do you have a happy brain?


The stress a woman feels during pregnancy can affect the developing brain of her unborn child as documented on fetal brain scans, according to a new study published Monday in the medical journal JAMA Open Network.

Stress during pregnancy may harm unborn baby's brain, studies find | CNN (10)

An expectant mother's stress can impact fetal brain development, a new study found.

Fetuses of expectant moms with higher anxiety levels were more likely to have weaker connections between two brain areas involved in executive and higher cognitive functions and stronger connections between parts of the brain connected to emotional and behavioral controls.

The study echoes other recent research that has found a direct impact of maternal stress on a baby’s future development.

“Toxic levels of anxiety … appear to be having direct effects on the way the fetal brain is being sculpted and organized in utero,” said study author Catherine Limperopoulos, who directs the Developing Brain Institute at Children’s National in Washington, DC.

“What the expectant mother is experiencing, the unborn baby is experiencing as well,” Limperopoulos said.

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A “toxic” level of anxiety in the study was defined as stress at levels that would interfere with a woman’s ability to successfully go about her day-to-day roles and responsibilities, but not enough to be clinically diagnosed as a mental health illness or disorder.

Stress causes the pituitary and adrenal glands to flood the body with “fight-or-flight” hormones originally meant to help us escape from wild animals and other dangers. Today, we live with chronic stress, and those chemicals, which include the stress hormone cortisol, have the ability to cross the placental barrier between mom and baby.

The link between stress and fetal brain development is especially disturbing for women who are pregnant during the pandemic, Limperopoulos said, as her prior research has found stress for pregnant women in the era of Covid-19 has doubled or even tripled.

“And there’s other published studies confirming that pregnant women are reporting very high levels of stress during the pandemic,” she said.

Courtesy Raquel Minina Parents and other caregivers are more stressed and in poorer health due to pandemic, report finds

“There’s a critical take-home message here,” Limperopoulos added. “It is really important that we are alerting women to the fact that high levels of stress may have an effect on their baby’s development and direct them to resources that can help them better manage their stress during this pandemic and beyond.”

The impact of maternal stress

Prior research has linked stress, anxiety and depression in pregnant mothers to social, emotional and behavioral problems in their offspring at later ages.

Smile and let go a little -- learning to not be so hard on yourself can lead to a healthier lifestyle. Exercise, eat right, get good sleep: The top 3 ways to prevent so many diseases

Clinical studies have found neurobehavioral deficits, such as impaired motor coordination, higher emotional reactivity and language delays in children born to stressed mothers.

(Video) Mother's stress can 'harm' unborn babies | Today Show Australia

Limperopoulos published a study earlier this year that found high levels of stress during pregnancy impaired a baby’s brain biochemistry and the growth of the hippocampus – the area of the brain involved in the formation of new memories, which is also associated with learning and emotions.

Prior studies have also found unusual electroencephalographic patterns in the frontal lobes of children, along with changes in the white matter responsible for organizing communication between the various parts of the brain.

Stress has also been linked to preterm birth. Women who felt overwhelmed and unable to cope during the months and even years before conception had shorter pregnancies than other women, according to a study published in July.

“Every day in the womb is important to fetal growth and development,” said senior author Christine Dunkel Schetter, a distinguished professor of psychology and psychiatry who has researched the topic for years at the Stress Processes and Pregnancy Lab at the University of California, Los Angeles.

“Premature infants have higher risk of adverse outcomes at birth and later in life than babies born later, including developmental disabilities and physical health problems,” Dunkel Schetter said.

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Another study published this month found that maternal stress – even before conception – can shorten the length of a baby’s telomeres, the compound DNA structures located at the tips of our chromosomes. responsible for protecting our cells from aging as they multiply.

Think of telomeres as the protective plastic caps on the ends of your shoelaces. Shortened telomeres have been linked to a higher risk of heart disease, cancers and earlier death.

“What our research tells us is that we may have early environmental and maternal factors influencing where a person starts in life, which may set them on course to age faster,” said lead author Judith Carroll, an associate professor of psychiatry and biobehavioral sciences at the Semel Institute for Neuroscience and Human Behavior at UCLA, in a statement.

Stress among low-risk pregnancies

The latest study in JAMA Open Network analyzed the stress levels of 50 women whose pregnancies were between 24 and 39 weeks and considered low risk due to the expectant mothers’ higher sociodemographic category. These well-educated, professional women were already healthy “control” volunteers in a larger study on fetal brain development. None of the women were on medication.

Close-up of a child playing on a touch screen tablet. Getty Images MRIs show screen time linked to lower brain development in preschoolers

On the same day the women filled out widely used and validated stress, anxiety and depression questionnaires, researchers took highly sensitive brain scans of their developing babies.

“These are considered safe studies – they do not harm the expectant mom or the fetus,” Limperopoulos said. “Hopefully we might be able to then use this kind of technology as an early preventative technique in a pregnancy. That’s what we’re hoping for.”

The study is following the mothers and babies until the children are 18 months of age, Limperopoulos said, to see if the effects during pregnancy are modified by environmental factors. And she is enrolling women in a future study to investigate if behavioral interventions can reduce an expectant mom’s symptoms.

“And importantly, are we able to measure preventable effects or restorative effects for the fetus before birth,” she said.

What’s important to take away from the study is that the risk factors of stress, anxiety and depression are modifiable, Limperopoulos emphasized, yet “75% of women who are experiencing mental health problems during pregnancy go undetected because we’re not systematically screenings for these problems.”

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“We really need to be paying attention to mental health problems during pregnancy, because they’re not only affecting the pregnant women but they seem to have enduring effects on the baby in the months and probably years down the line,” Limperopoulos added.

“If we as a society can make changes to help give pregnant women the resources they need and provide them with a safe and supportive environment before and during pregnancy, we may have a significant impact on the health of their children,” Carroll said.

(Video) Dr. Catherine Monk: The Mother-Infant Relationship Before Birth & Why it Matters

(Video) Stress during pregnancy: does stress affect fetal and child health?


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